The Detroit Pistons and Cleveland Cavaliers gear up for an intense Game 1 in their Eastern Conference Playoffs series on Tuesday, following their hard-fought victories in Game 7s. Both teams showcased resilience to advance to this stage of the 2026 NBA playoffs.

These two squads faced each other four times during the regular season, splitting the series with each team winning once at home. Tipoff is set for 7 p.m. ET at Little Caesars Arena, where the Pistons enter as a 3.5-point favorite according to the latest odds from FanDuel Sportsbook. The over/under for total points is set at 215.5.

Before placing any bets on this matchup, it’s vital to consider insights from the SportsLine Projection Model, which has built a reputation for accuracy, having returned over $10,000 in profit for $100 players over the past eight-plus seasons. This season, the model has an impressive 26-9 record (74%) on top-rated NBA spread picks.

Key betting lines include:

• Spread: Pistons -3.5 at FanDuel
• Over/Under: 215.5 points
• Money Line: Pistons -147, Cavaliers +120

According to the model's simulations, the total points scored is projected to be 214, making the Under a strong prediction, hitting in 52% of simulations. Additionally, the Under has been a trend for the Pistons, with 54% of their games this season going below the total.

For those looking to capitalize on betting opportunities, SportsLine recommends checking its detailed predictions and picks. Don't miss the chance to see how each side of the spread performs, with one side hitting nearly 60% of the time in the model’s simulations.