The NBA playoff rivalry intensifies as Joel Embiid and the Philadelphia 76ers face off against Jalen Brunson and the favored New York Knicks in the second round of the 2026 Eastern Conference Playoffs. Following a decisive 137-98 victory for the Knicks in Game 1, the teams prepare for Game 2 at Madison Square Garden on Wednesday night.

Game Details:

• Date: Wednesday
• Time: 7 p.m. ET
• Location: Madison Square Garden

The Knicks, holding the No. 3 seed in the East, are favored to win again, currently sitting at -6.5 in the latest odds from FanDuel Sportsbook. The over/under for total points is set at 215.5. Notably, the regular season saw both teams split their matchups, each winning twice on their home courts.

The SportsLine Projection Model, which has proven successful with a 74% winning rate on top-rated NBA spread picks this season, has simulated this matchup 10,000 times. This model has generated over $10,000 in betting profit for $100 players in the past eight-plus seasons.

Key Predictions:

• Spread: Knicks -6.5
• Over/Under: 215.5 points
• Money Line: Knicks -274, 76ers +221

The model projects a combined total of 220 points, indicating the Over hits in 56% of simulations. This suggests that, even though the Knicks may not replicate their 140-point performance from Game 1, the 76ers are unlikely to be held to just 98 points again.

For those interested in betting, the model strongly recommends considering the Over for this matchup, making it an appealing option for NBA parlay betting. For a deeper analysis and specific picks, fans can check out the insights available at SportsLine.