The Week 4 NFL schedule features several exciting matchups, including the highly anticipated Raiders vs. Chiefs clash, where Kansas City stands as a 4.5-point favorite. The over/under for this game is set at 47.5. Another notable game is 49ers vs. Broncos, with San Francisco favored by 3 points and an over/under of 46.5.

The SportsLine Projection Model has simulated each matchup 10,000 times to provide insights and predictions for all 16 NFL games this week. Here are some highlighted predictions:

• Thursday, Oct. 1
  Steelers (-2.5) vs. Browns
  Score Prediction: Steelers 21, Browns 16
  Steelers cover as 2.5-point favorites in 59% of simulations.

• Sunday, Oct. 4
  Commanders vs. Colts (-3.5)
  Score Prediction: Colts 32, Commanders 27
  Colts cover as 3.5-point favorites in 53% of simulations.

• Giants vs. Cardinals (-1)
  Score Prediction: Cardinals 25, Giants 23
  Cardinals cover as 1-point favorites in 51% of simulations.

• Bills (-6.5) vs. Patriots
  Score Prediction: Bills 28, Patriots 20
  Bills cover as 6.5-point favorites in 52% of simulations.

• Ravens (-11.5) vs. Titans
  Score Prediction: Ravens 34, Titans 20
  Ravens cover as 11.5-point favorites in 56% of simulations.

• Monday, Oct. 5
  Saints (-2.5) vs. Falcons
  Score Prediction: Saints 25, Falcons 24
  Falcons cover as 2.5-point underdogs in 52% of simulations.

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