Wales faced a crushing defeat against South Africa, losing 43-0 in the Nations Championship on October 14 in Durban. This match marked another disappointing outing for Wales, who previously suffered a 73-0 loss to the Springboks in November.

South Africa showcased their dominance by scoring seven tries from players including Jasper Wiese, Cobus Reinach, Jesse Kriel, Jaco Williams, Herschel Jantjies, Kurt-Lee Arendse, and Paul de Villiers. Newcomers Vusi Moyo and Marnie Libbok contributed with four successful conversions between them. Despite having more experienced players in their lineup, Wales struggled to match the power and intensity of the Springboks.

The game started ominously for Wales, as they quickly fell behind.

• Wiese scored within the first five minutes.
• Reinach added to the score after another dominant scrum, with Moyo converting.
• Wales' defense held off further tries until the end of the first half, when Kriel capitalized on a cross-kick from Moyo.

The second half saw Jaco Williams score just 40 seconds in, taking full advantage of a loose Wales kick. Wales showed brief signs of life, with Ellis Mee nearly crossing the line, but they failed to convert opportunities into points.

As the match progressed, Wales faced further setbacks, including a yellow card for Ben Warren. South Africa took full advantage of their numerical superiority, with Arendse and De Villiers sealing the score. This victory marked the Springboks' 11th consecutive win and solidified their top position in the Southern Section of the championship.