The Seattle Seahawks embark on their title defense against the New England Patriots in the 2026 NFL Kickoff Game at 8:20 p.m. ET on Wednesday. Following a stellar 2025 season where they clinched their second Super Bowl championship, the Seahawks aim to continue their winning momentum at Lumen Field.

Last season, the Seahawks finished with a franchise-record 14 wins and triumphed over the San Francisco 49ers and Los Angeles Rams in the playoffs, ultimately defeating the Patriots 29-13 in Super Bowl LX. The matchup is expected to be high-scoring, as both teams ranked among the top three in points per game last season, with New England averaging 28.8 and Seattle 28.4.

Key Player Changes:

• New England's Rhamondre Stevenson steps up as the primary running back, replacing the injured TreVeyon Henderson.
• Seattle's rookie Jadarian Price takes on a significant role following the offseason loss of Kenneth Walker III.

Notable Additions:

• The Patriots bolstered their offense with A.J. Brown, while the Seahawks feature star receivers Jaxon Smith-Njigba and Cooper Kupp.

In Major League Baseball, ten games highlight the Wednesday schedule, including:

• Milwaukee Brewers vs. Chicago Cubs at 7:40 p.m. ET: The Brewers, leading the division, aim for a sweep.
• Los Angeles Dodgers vs. Cincinnati Reds at 10:10 p.m. ET: The Dodgers seek their seventh consecutive win.
• Boston Red Sox vs. Los Angeles Angels at 6:45 p.m. ET: The Red Sox look to rebound after a recent loss.
• New York Yankees vs. Colorado Rockies at 7:05 p.m. ET: Yankees chase a division title.

Betting odds favor the Seahawks by 3 points, with the Dodgers and Red Sox also seen as significant favorites in their respective matchups. Fans can catch all the action on various platforms, including NBC/Peacock for the NFL game and MLB.TV for baseball.