The Kansas City Chiefs seek to turn around their fortunes as they host the Denver Broncos on Monday Night Football, September 14, 2026, at 8:15 p.m. ET. This matchup marks the end of Week 1 of the NFL season and the return of Patrick Mahomes, who is back after a nine-month recovery from a torn ACL. The Chiefs, who suffered a disappointing 6-11 season last year, are looking to break a three-game losing streak against the Broncos.

Key Details:

• Teams: Kansas City Chiefs vs. Denver Broncos
• Location: Arrowhead Stadium, Kansas City
• TV: ABC/ESPN
• Betting Odds: Chiefs favored by 2 points

Last season, the Chiefs finished with their first losing record since 2012, missing the playoffs for the first time since 2014. Mahomes' absence was felt deeply as the team ended the previous season on a six-game losing streak.

On the other side, the Broncos, led by Bo Nix, also welcome back their star quarterback, who returns after a broken ankle sidelined him during the playoffs. Denver concluded last season with an impressive 14-3 record, ending the Chiefs' nine-year dominance in the AFC West.

In addition to the NFL action, several MLB games are also on the schedule:

• Chicago White Sox (76-73) at Cleveland Guardians (76-74) at 6:40 p.m. ET
• Toronto Blue Jays (75-75) hosting Detroit Tigers (70-79) at 7:07 p.m. ET
• Chicago Cubs (83-67) facing Atlanta Braves (88-62) at 7:40 p.m. ET
• San Diego Padres (81-68) against Colorado Rockies (55-94) at 8:40 p.m. ET

With both leagues showcasing intense matchups, fans are set for an exciting night of sports. Betting insights suggest the Guardians are -155 favorites against the White Sox, while the Blue Jays are -137 over the Tigers. The Cubs and Padres also enter their games as betting favorites, promising thrilling action for all sports enthusiasts.