Several key divisional and conference matchups highlight Week 8, despite four teams having byes: the Texans, Saints, Giants, and 49ers. Among the top divisional games are:

• Vikings vs. Lions (-3)
• Falcons vs. Buccaneers (-1.5)
• Browns vs. Steelers (-3.5)
• Colts vs. Jaguars (-7.5)
• Chiefs vs. Broncos (+1.5)
• Patriots vs. Dolphins (+7.5)
• Eagles vs. Commanders (-3.5)

Key intraconference matchups include:

• Ravens vs. Bills (-3.5)
• Cardinals vs. Cowboys (-6.5)

The week wraps up with a 'Monday Night Football' clash between the defending NFC North champion Chicago Bears and the defending Super Bowl champion Seattle Seahawks (-3). The Seahawks have historically dominated this matchup, winning four of the last six encounters, including a 6-3 victory in their last meeting in 2024.

Before making any Week 8 NFL picks or score predictions, consider the insights from the self-learning SportsLine AI. This advanced AI, developed by SportsLine's Data Science team, evaluates each game based on historical data and opponent strengths, continuously updating its predictions.

For Week 8, SportsLine AI projects a 31-28 win for the Patriots over the Dolphins. The Patriots, currently second in the AFC East at 4-3, face a struggling Dolphins team at 1-5, coming off a narrow victory against the Jets.

Dolphins’ Key Player:

• Malik Willis: 57.6% completion rate, 1,057 yards, 4 TDs, 4 INTs, and 3 rushing TDs.

Patriots’ Key Player:

• Drake Maye: 65.9% completion rate, 1,784 yards, 13 TDs, 8 INTs.

SportsLine AI predicts the total to go Over (44.5) and suggests the Dolphins (+7) as a strong value pick. For more insights and predictions, check out SportsLine’s comprehensive NFL analysis.