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Reds vs. Guardians odds, prediction, time: 2026 MLB picks for Tuesday, July 28 by proven model

Guardians and Reds Clash in Key Doubleheader Showdown

CBS Sports•
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AI Summary

The Cleveland Guardians and Cincinnati Reds face off in Game 1 of a doubleheader on Tuesday, July 28, following a rainout on Monday. The Guardians, sitting at 54-53, trail the Chicago White Sox by two games in the AL Central, while the Reds, with a record of 49-55, find themselves at the bottom of the NL Central and are expected to be sellers at the upcoming trade deadline.

Starting for Cincinnati is ace Chase Burns, boasting a record of 12-1 with a 2.42 ERA, while Slade Ceconni (4-7, 3.60 ERA) takes the mound for the Guardians. The first pitch is scheduled for 1:40 p.m. ET at Great American Ball Park.

In the latest odds, the Reds are favored at -164 (risk $164 to win $100), with an over/under set at 9 runs. Before placing any bets, it’s essential to consider insights from SportsLine's proven computer model, which has simulated this matchup 10,000 times and has been on a 39-23 run for top-rated MLB picks.

Betting Lines:

  • Money Line: Reds -164, Guardians +137
  • Over/Under: 9 runs
  • Run Line: Reds -1.5 (+119)

Model Predictions:

After extensive simulations, the model predicts the total runs will go Under 9, as both teams have recently trended towards lower scoring games. Cincinnati has seen five consecutive games hit the Under, while Cleveland has a 54% Under rate this season, increasing to 58% on the road.

Chase Burns is currently among the top five in NL Cy Young odds, and the model estimates 8.1 combined runs for this matchup, hitting the Under 57% of the time. For further insights and picks, visit SportsLine for the best value on the money line.

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