Professional rugby returns to St Helen's as the Ospreys and Dragons face off in a highly anticipated derby in the United Rugby Championship (URC). Scheduled for Saturday at 19:00 BST, this match marks the Ospreys' first home fixture of the season at their revamped ground in Swansea.

The clash features 10 players from the Wales squad, all set to play their final games before joining the national team for the Nations Championship. The Ospreys field all four of their Wales internationals:

• Tom Rogers (full-back)
• Dan Edwards (fly-half)
• Reuben Morgan-Williams (scrum-half)
• Gareth Thomas (loose-head prop)

Meanwhile, the Dragons include six players:

• Rio Dyer (wing/full-back)
• Aneurin Owen (centre)
• Dillon Lewis (tight-head prop)
• Ben Carter (lock)
• Seb Davies (lock)
• Che Hope (scrum-half, bench)

The Ospreys have made strategic rotations due to a demanding schedule, which included matches against the Sharks, Lions, and Black Lion. Their recent encounter with the Dragons resulted in a thrilling 38-31 victory, showcasing their strong lineup.

In terms of changes, coach Mark Jones has made one adjustment to the pack, bringing back Harri Deaves while Ross Moriarty moves to the bench. The backs will feature Morgan-Williams, Owen Watkin, and Iestyn Hopkins, with Lalakai Foketi remaining a substitute after a notable performance in Newport.

As the Ospreys aim for a double over the Dragons, this sold-out fixture at St Helen's is a return to their roots, having originally played there from 2003 to 2005. Following this derby, the Ospreys will face Cardiff on 31 October.