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NFL Week 5 picks: Experts face off on Buccaneers at Cowboys, 49ers at Seahawks and more

Experts Weigh In: NFL Week 5 Predictions Featuring Key Matchups and Insights

CBS Sports•
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Summary

As the 2026 NFL regular season reaches its fifth week, excitement builds with several thrilling matchups on the horizon. Highlights include the Philadelphia Eagles facing the Jacksonville Jaguars in London, the San Francisco 49ers visiting the reigning Super Bowl champions, the Seattle Seahawks, and a highly anticipated Monday Night Football clash between Josh Allen and Matthew Stafford.

Recent statistics reveal that 23 games were decided by one score over the past two weeks, marking a record-setting pace. With 18 games this season decided by a game-winning score in the final four minutes or overtime, fans can expect more nail-biting action in Week 5.

Key Matchup Predictions:

  • Tampa Bay Buccaneers at Dallas Cowboys (-8.5)

    • Jordan Dajani predicts a Cowboys victory, 30-20, emphasizing their offensive strength.
    • Jared Dubin agrees, forecasting a Cowboys win, 34-17, citing the Bucs' struggles.
  • Philadelphia Eagles vs. Jacksonville Jaguars (-7) (London)

    • Dajani believes the Jaguars will triumph, 27-18, as the Eagles struggle with injuries.
    • Dubin anticipates a close game, predicting a Jaguars win, 23-17, but expects the Eagles to cover.
  • Chicago Bears (-3) at Green Bay Packers

    • Dajani favors the Packers, 21-20, despite their poor performance.
    • Dubin sees a competitive game, predicting a Bears victory, 23-20.
  • Indianapolis Colts at Pittsburgh Steelers (-2.5)

    • Dajani picks the Steelers, 24-17, citing their historical dominance over the Colts.
    • Dubin predicts an upset with the Colts winning, 20-16.
  • San Francisco 49ers at Seattle Seahawks (-2.5)

    • Dajani expects the 49ers to win, 24-23, praising Brock Purdy's performance.
    • Dubin foresees a Seahawks victory, 24-21, emphasizing their strong defense.
  • Baltimore Ravens at Atlanta Falcons (-3.5) (SNF)

    • Both experts predict the Falcons will win, with scores of 27-21 and 24-17, respectively, particularly if Lamar Jackson doesn't play.
  • Buffalo Bills at Los Angeles Rams (-3) (MNF)

    • Dajani believes the Bills will pull off an upset, 30-27, highlighting their scoring ability despite recent struggles.

With all these predictions, fans are eager to see how the games unfold this week, as the NFL continues to deliver excitement and drama.

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