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NFL Week 5 picks and score predictions: Ravens and Bills both lose, 49ers win thriller over Seahawks

NFL Week 5 Predictions: Upsets Loom as Ravens, Bills Face Tough Challenges

CBS Sports•
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Summary

As the NFL Week 5 unfolds, the excitement builds with several key matchups that could shift the dynamics of the season. Fantasy football woes plague many, including the writer, who humorously admits to a jinx that seems to follow drafted players like Saquon Barkley, currently on the trade block.

Key Matchups:

  • Raiders (3-1) at Patriots (2-2)
    The unpredictable Drake Maye leads the Patriots against a Raiders team that struggles against the run. The prediction leans toward a Patriots victory, 27-24.

  • Bears (3-1) at Packers (2-2)
    With the Packers' shaky start, the pressure mounts. The Bears are expected to win 30-23, capitalizing on the Packers' offensive struggles.

  • 49ers (4-0) at Seahawks (3-1)
    The undefeated 49ers face a tough Seahawks defense, but with Brock Purdy performing at a high level, they are predicted to edge out Seahawks with a 27-24 win.

  • Ravens (3-1) at Falcons (2-2)
    The banged-up Ravens, led by Lamar Jackson, may struggle against a resurgent Falcons team, making the prediction Falcons 30-27.

  • Bills (3-1) at Rams (2-2)
    A critical matchup for both teams, the Bills face a tough challenge against the Rams. With concerns over their defense, the prediction favors the Rams 34-31.

Additional Predictions:

  • Cowboys 27-17 over Buccaneers
  • Jaguars 30-20 over Eagles
  • Bengals 24-16 over Dolphins

With the stakes high in Week 5, the outcomes could significantly impact playoff aspirations. Fans eagerly await to see if these predictions hold true.

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