As the 2026 NFL Kickoff Game approaches, featuring the Seattle Seahawks against the New England Patriots on Wednesday, September 9 at 8:20 p.m. ET, daily Fantasy players are gearing up for an exciting matchup. The Seahawks enter as 3.5-point favorites with an over/under of 44.5 points, bringing a mix of familiar faces and newcomers into the DFS spotlight.

Key players from Super Bowl 60, including Sam Darnold, Drake Maye, and Jaxon Smith-Njigba, are expected to play pivotal roles, while fresh talents like A.J. Brown, Romeo Doubs, and Jadarian Price aim to leave their mark. Notably, undervalued players like Tory Horton and Mack Hollins may prove crucial in constructing winning lineups.

Mike McClure, a renowned DFS expert with over $2 million in career winnings, has shared his insights for this matchup. Utilizing a sophisticated prediction model, McClure evaluates matchups, statistical trends, and injuries to identify top DFS values. His proven track record includes impressive finishes in high-stakes tournaments.

Among his top picks:

• A.J. Brown: The three-time Pro Bowler is set to make a splash with the Patriots, having previously posted 155 yards in his Eagles debut. Despite the Seahawks' strong defense, they struggled against opposing wideouts, making Brown a reliable DFS option.

• Jadarian Price: With Kenneth Walker III now with the Kansas City Chiefs and Zach Charbonnet sidelined, Price is poised to take on a significant workload. The first-round draft pick had an impressive college career, and he faces a Patriots defense that allowed the sixth-most Fantasy points to running backs in 2025.

McClure emphasizes the importance of strategic lineup construction, especially considering potential breakout players. For more exclusive picks and DFS strategies, fans can check out McClure's insights at SportsLine.