The Kansas City Chiefs kick off their 2025 season aiming to return to form after missing the postseason for the first time in over a decade. They face off against the defending AFC West champion Denver Broncos on Monday Night Football, with kickoff set for 8:15 p.m. ET at GEHA Field at Arrowhead Stadium in Kansas City, Missouri.

This matchup marks the return of Chiefs quarterback Patrick Mahomes, who missed a significant portion of last season due to a torn ACL and MCL. The Chiefs, who finished third in the AFC West with a 6-11 record last season, look to improve against the Broncos, who boasted an impressive 14-3 record, tying for the best in the NFL.

Key Game Details:

• Spread: Chiefs -2.5
• Over/Under: 43.5 points
• Money Line: Chiefs -134, Broncos +113

Brady Kannon, a Vegas-based expert, has performed well this season, finishing 41-31-2 (+7.95 units) and entering this game on a 32-15 run with NFL picks, returning $1,648 to $100 players. Kannon emphasizes that points may be scarce in this matchup due to several factors: the Broncos' strong defense and Mahomes' potential slow start as he regains his form.

Kannon noted, "Much of the love for the Broncos this offseason is related to their excellent defense. Kansas City has lost some key players in the secondary, but Coach Spagnuolo will likely have his side ready for this primetime game."

As predictions roll in, Kannon leans towards the Under 43.5 total points. For those looking to make informed bets, Kannon’s insights, along with other expert picks, are available at SportsLine.