The Seattle Mariners and Detroit Tigers clash in a crucial Game 2 of their three-game American League series on Saturday, June 6. After the Tigers' impressive 7-3 victory over the Mariners on Friday, both teams are looking to extend their winning streaks. The Mariners, currently sitting at 33-31, have won eight of their last 10 games and hold a 14-15 record on the road this season. Meanwhile, the Tigers, with a 26-38 record, have captured four consecutive wins and are 15-14 at home in 2026.

First pitch is scheduled for 1:10 p.m. ET at Comerica Park in Detroit. Historically, the Tigers lead the all-time series 237-218, but the Mariners have triumphed in seven of the last 10 meetings. In the latest odds, Seattle is a -135 favorite on the money line, while the over/under stands at 8.5 runs.

The SportsLine Projection Model, which simulates every MLB game 10,000 times, is currently on a red-hot 17-5 run (77%) for top-rated MLB picks. It has also shown significant success with home run prop picks in 2025, yielding nearly 30 units of profit.

Key betting lines for this matchup include:

• Mariners vs. Tigers money line: Mariners -135, Tigers +113
• Over/Under: 8.5 runs
• Run line: Mariners -1.5 (+124)

The model predicts the total runs will exceed 8.5, as the Over has hit in six of the past 10 matchups between these teams. Additionally, the Over has been successful in six of the last ten games for Seattle and three of the last four for Detroit.

Projected players for total bases include Mariners' Randy Arozarena, Julio Rodriguez, Brendan Donovan, and Dominic Canzone, while the Tigers' Riley Greene, Kevin McGonigle, and Kerry Carpenter are also expected to contribute. The model forecasts 9.1 combined runs, affirming the Over's value.

For those looking to make informed bets, the model highlights one side of the money line as particularly valuable, available at SportsLine.