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Guardians vs. White Sox prediction, odds, time: 2026 ALDS Game 2 picks by proven model

Guardians Aim to Bounce Back in ALDS Game 2 Against Surging White Sox

CBS Sports•
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Summary

The 2026 MLB playoffs continue on Monday with a crucial Game 2 in the ALDS, featuring the Cleveland Guardians hosting the Chicago White Sox. After a surprising postseason run, the White Sox look to build on their momentum following a 3-0 victory in Game 1.

Starting Pitchers:

  • Anthony Kay (Chicago White Sox): 10-9 record, 4.44 ERA
  • Gavin Williams (Cleveland Guardians): 14-8 record, 3.76 ERA

Game Details:

  • Date: Monday
  • Time: 5 p.m. ET
  • Location: Progressive Field, Cleveland

In the latest odds, Cleveland is favored at -154 (risk $154 to win $100), while the over/under is set at 6.5 runs. The SportsLine Projection Model, which has successfully simulated every MLB game 10,000 times, has been performing well, boasting a 31-25 record on top-rated money-line picks, yielding over $900 for $100 players.

Key betting lines for the matchup include:

  • Money Line: Guardians -154, White Sox +135
  • Run Line: Guardians -1.5 (+152)

Model Predictions:

  • The model predicts the total runs will exceed 6.5, based on strong offensive trends for the White Sox, who scored 13 runs in their wild-card series against the Astros. In 58% of their games this season, they have surpassed the total runs.
  • Historical matchups favor the over, with eight of 14 games this season clearing the total, including all three games during their mid-September series.

For those looking to make informed bets, the model suggests one side of the money line offers significant value, which can be found at SportsLine.

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