The Cleveland Guardians prepare to host the Chicago White Sox in a pivotal Game 5 of the American League Division Series on Saturday night at Progressive Field. The stakes are monumental, with the winner advancing to face the Tampa Bay Rays in the ALCS, while the loser concludes their 2026 season.

The White Sox will put their faith in right-hander Sean Burke, their ace from the regular season. In response, the Guardians will start right-hander Gavin Williams, who led the American League with 248 strikeouts during the regular season. Manager Stephen Vogt's choice of Williams comes after rookie Parker Messick pitched in Game 4.

Notably, Williams recently pitched in relief during the Guardians' Game 4 victory in Chicago. This quick turnaround means that he will become the sixth pitcher since 1945 to record the last out of one game and then start the next game in the same postseason series. The pitchers he joins include:

• Jesse Chavez, Braves (2021 NLCS)
• Brad Peacock, Astros (2019 ALCS)
• Miguel Batista, Diamondbacks (2001 NLDS)
• Bob Turley, Yankees (1957 WS)
• Hank Borowy, Cubs (1945 WS)

Among these, only Batista's 2001 NLDS start is somewhat comparable, as he pitched six innings with four strikeouts.

Manager Vogt seeks length from Williams, who is expected to face the lineup at least once or twice. Williams previously faced the White Sox in Game 2, striking out 11 batters and allowing two runs on four hits. His historic opportunity looms as he steps onto the mound for this decisive clash.