The Kansas City Chiefs aim to maintain their undefeated record as they face the defending Super Bowl champion Seattle Seahawks on Sunday Night Football. Kansas City comes off a solid 22-6 victory against the Los Angeles Chargers, while Seattle suffered a narrow 17-14 overtime loss to Denver on October 15.

Currently, the Chiefs lead the AFC West with a 5-0 record, including a perfect 2-0 on the road this season. Conversely, the Seahawks sit at 3-3, having lost two consecutive games and holding second place in the NFC West with a 2-1 home record in 2026.

Kickoff is slated for 8:20 p.m. ET at Lumen Field in Seattle. Historically, Kansas City leads the all-time series 34-19, winning four of their last five encounters. The latest betting odds show Seattle as a 3-point favorite, with an over/under set at 42.5 points.

Before placing any bets, it's crucial to consider insights from SportsLine's proven model, which simulates every NFL game 10,000 times. This model has yielded over $5,000 in profits for $100 players since its inception, showcasing a 58-48 record on top-rated picks since 2024.

For this matchup, the model predicts:

• Spread: Seahawks -3
• Over/Under: 42.5 points
• Money Line: Seahawks -148, Chiefs +130

Notably, the model favors the Over hitting at 55% probability, with a projection of 46 combined points. The Chiefs boast the fifth-highest scoring offense, averaging 28 points per game, while the Seahawks average 24.7 points. Quarterback Patrick Mahomes leads Kansas City, having thrown for 1,309 yards and nine touchdowns. Meanwhile, Sam Darnold guides Seattle with 1,033 yards and seven touchdowns, albeit with seven interceptions.

For detailed predictions and betting strategies, check out SportsLine's expert analysis.