An AFC West rematch with significant division implications unfolds in NFL Week 8 as Bo Nix and the Denver Broncos host Patrick Mahomes and the Kansas City Chiefs. The game airs on CBS and Paramount+, kicking off at 4:25 p.m. ET from Empower Field at Mile High in Denver.

The Chiefs (5-1) are coming off their first loss of the season, suffering a 20-3 defeat at Seattle, while the Broncos (5-2) have surged with three consecutive victories. Notably, the Broncos have triumphed in their last three meetings at home against the Chiefs, including a decisive 31-10 win in Week 1.

In terms of betting, the latest odds favor Kansas City by 1.5 points, with an over/under set at 40.5 points. Before placing any bets, it’s crucial to consult predictions from SportsLine's advanced model, which simulates every NFL game 10,000 times and has shown a profit of over $5,000 for $100 players on top-rated NFL picks since its inception.

Key betting lines include:

• Chiefs vs. Broncos spread: Chiefs -1.5
• Over/Under: 40.5 points
• Money line: Chiefs -118, Broncos -102

The model predicts the game will trend Under 40.5 points, reflecting the teams' recent performances: the Broncos have gone 5-2 on the Under, while the Chiefs have limited three of their six opponents to 10 points or less. With both teams focusing on a run-first approach, the projected combined score is 40 points, indicating strong value in the Under.

For those interested in making informed picks, the model also highlights one side of the spread hitting over 50% of the time. Check SportsLine for the latest insights.