Alexander Isak made a triumphant return from injury, scoring the decisive goal as Liverpool staged a comeback to defeat Brentford 2-1 on October 1. The match saw Yehor Yarmoliuk and Vitaly Janelt sent off, significantly impacting Brentford's chances.

Brentford initially took the lead with a header from Keane Lewis-Potter, just moments after a penalty awarded to Liverpool was overturned. However, the game turned in first-half stoppage time when Yarmoliuk received a straight red card for headbutting Jeremy Jacquet. Referee John Brookes, after consulting the VAR, deemed it violent conduct.

Following the red card, Liverpool capitalized on their numerical advantage in the second half:

• Victor Munoz equalized with a well-placed shot, assisted by Florian Wirtz.
• Isak then scored the winner, converting a knockdown from Bradley Barcola.

As the match progressed, Brentford missed a crucial opportunity to level the score when Igor Thiago failed to convert from close range. The situation worsened for Brentford when Janelt received a second yellow card for a foul on Rio Ngumoha in stoppage time, leaving them with nine men.

The victory propelled Liverpool to fifth place in the league, while Brentford suffered their first defeat of the season. However, the match was not without its own challenges for Liverpool, as Dominik Szoboszlai and Jeremie Frimpong both sustained injuries, raising concerns for their upcoming fixtures.