The Chicago Bears face the defending Super Bowl champion Seattle Seahawks in a pivotal NFC matchup on Monday Night Football. The game kicks off at 8:15 p.m. ET from Lumen Field in Seattle. Chicago enters the contest after a 30-24 victory over the New England Patriots on October 22, while Seattle secured a 20-3 win against Kansas City in Week 7.

Currently, the Bears hold a 5-2 record, placing them second in the NFC North, and they are 2-1 on the road this season. In contrast, the Seahawks stand at 4-3, also second in the NFC West, with a 3-1 home record in 2026. Notably, the Bears will miss tight end Cole Kmet, who suffered a season-ending knee injury.

Seattle leads the all-time series 12-8, although Chicago has triumphed in two of their last three encounters. As for betting odds, Seattle is favored by 3 points, with an over/under set at 46.5 points. Defensive tackle Jeffery Simmons is expected to make his debut for the Bears after being traded from the Titans.

The SportsLine model, which simulates every NFL game 10,000 times, has shown strong returns, outperforming by over $5,000 for $100 players on top-rated NFL picks. The model has also predicted that the game will go over 46.5 points, a trend supported by recent matchups.

Key player stats include:

• Caleb Williams (Bears QB): 71% completion rate, 1,020 yards, 5 touchdowns, 1 interception in four starts.
• Sam Darnold (Seahawks QB): 62.1% completion rate, 1,290 yards, 8 touchdowns, 8 interceptions in six starts.

The model projects a total of 48 points, indicating a 51% chance of hitting the over. For those interested in betting, the model also highlights a side of the spread that hits over 60% of the time. Check SportsLine for further insights and predictions.