As Week 2 of the NFL season approaches, making accurate score predictions proves challenging, especially with key matchups like the Panthers vs. Falcons. The Carolina Panthers have a history of scoring 30 points in both encounters last season, showing a consistent offensive capability with 30 or 31 points in five of their last 17 games.

The Panthers enter the game as a 1.5-point road favorite, with an over/under set at 43.5. This matchup is among five divisional games to consider for betting alongside:

• Bears vs. Vikings (+5.5, 48.5)
• Chargers vs. Raiders (+7, 43.5)
• Cowboys vs. Commanders (+3.5, 50.5)
• Seahawks vs. Cardinals (+4.5, 41.5)

Expert Eric Cohen has evaluated the entire Week 2 slate, finishing the previous season with a 66% straight-up record and currently holding a 63% success rate on his 2026 picks. His insights suggest that understanding both the spread and total can significantly enhance the chances of accurately predicting scores, potentially yielding massive returns.

Among his top picks, Cohen emphasizes the Cowboys (-3.5, 50.5) to defeat the Washington Commanders. With a remarkable 13-2 record against Washington when Dak Prescott is under center, the Cowboys are expected to leverage their home advantage. Despite the Commanders' ability to score against a historically weak Dallas defense, Cohen envisions a close contest:

"Expect a high-scoring affair, with the Cowboys likely to establish an early lead as the Commanders attempt a late comeback," Cohen stated, predicting a final score of Cowboys 34, Commanders 26.

Cohen also forecasts four teams to win by two touchdowns or more, making alternate lines enticing for bettors. For detailed predictions, fans can turn to SportsLine for the latest insights.